Brazil faces one of its worst dengue outbreaks in years, prompting health authorities to release genetically modified mosquitoes across multiple cities. Rather than depending solely on vaccines or insecticides, teams introduce lab-altered insects to gradually lower populations of disease-carrying mosquitoes. Although the tactic appears counterintuitive, the underlying method is straightforward. Officials report over one million cases in the first two months, more than double last year’s figure, with several cities declaring emergencies including Rio de Janeiro. Dengue spreads only via bites from infected female Aedes aegypti mosquitoes and cannot transmit directly between people. Roughly three-quarters of infections produce no symptoms, while others cause fever and nausea that resolve in about a week. Severe cases remain rare but can prove dangerous. The released mosquitoes, developed by Oxitec, carry a gene that kills female offspring before adulthood. Since only females bite and transmit the virus, the approach reduces vector numbers over successive generations, with prior trials showing up to 90 percent local declines. Eggs are placed in compact boxes that hatch in standing water, allowing adults to emerge and mate naturally. Similar releases occurred in the United States in 2021, and other nations have tested Wolbachia bacteria to limit transmission. Safety questions persist regarding possible gene transfer to wild populations, yet no human risks have been identified. Officials continue combining multiple strategies during the rainy season to manage rising cases.

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https://timesofindia.indiatimes.com/science/brazil-is-releasing-millions-of-genetically-modified-mosquitoes-to-fight-one-of-its-worst-dengue-outbreaks-in-years/articleshow/132327041.cms
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